該基因編碼的蛋白是成纖維細胞生長因子（fgf）家族的一員。fgf家族成員具有廣泛的有絲分裂和細胞存活活性，參與胚胎發育、細胞生長、形態發生、組織修復、腫瘤生長和侵襲等多種生物學過程。該基因突變與常染色體顯性遺傳性腦共濟失調有關。另外，已經發現該基因的剪接轉錄變體。[由RefSeq提供，2008年7月]
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]