該基因編碼一種與乙型肝炎病毒X蛋白（hbx）相互作用的核蛋白，并通過hbx轉錄激活劑促進乙型肝炎病毒基因的轉錄，提示這種相互作用在病毒生命周期中的作用。該蛋白也與snf2h蛋白相互作用，形成rsf染色質重塑復合物，其中snf2h亞單位作為核小體依賴性atpase，該蛋白作為組蛋白伴侶。
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone.